NanoSight provides a unique technology to visualise and size nano-scale particles in liquid down to 10nm with little preparation and at low cost. Based on a fundamental understanding of existing particle sizing techniques, the NanoSight technology has been developed into a unique and exciting instrument for nanoparticle sizing, available as both a research instrument and in a bench-top format. NanoSight have a growing customer base of diverse users worldwide
The Nanoparticle Tracking Analysis (NTA) technique is based on laser light scattering microscopy. The instruments can visualise and dynamically size populations of particles in a liquid on an individual basis in the particle size range of 10 nm – 1000 nm (dependent on material). The Brownian motion of each and every particle (which appear as point scatterers) is tracked separately but simultaneously using a CCD camera, from which a high resolution plot of the particle size distribution profile (and changes therein in time) is obtained. Sample pre-treatment is minimal and all particle types can be measured.
This particle-by-particle approach avoids the averaging assumptions of photon correlation spectroscopy (PCS, or dynamic light scattering DLS) and provides a unique image from which an independent quantitative estimation of sample size, size distribution and concentration can be immediately obtained.
